Pulmonary involvement in Lassa fever: a scoping review

INTRODUCTION: Lassa fever (LF) affects all body systems, however, inadequate knowledge exists on the involvement of pulmonary system in LF infections. This scoping review, therefore, aimed to describe LF. MATERIAL AND METHODS: We conducted an extensive search literature two databases, namely PubMed and Google Scholar. Overall, 5,217 articles were retrieved from a database search, out which 107 duplicates removed. 12 included: four review articles, three case reports, experimental inoculation studies, one retrospective study, prospective case-control study. RESULTS: Symptoms experienced included fever, pharyngitis, retrosternal pain, respiratory distress, proteinuria. Complications unique arteritis, embolization, mucosal bleeding, pleural or pericardial effusion, edema, interstitial pneumonitis. Consequences effect virus infection impairment immune alongside continual replication affected tissues death individuals. has varied but serious effects system. CONCLUSIONS: These symptoms, particularly areas where is known be endemic, should prompt clinicians request polymerase chain reaction for confirmatory diagnosis. features promote provision support patients need such.